The chart relates the activity and rest pattern that causes abnormality in the endorphins and cholecystokinin. Cholecystokinin secretion can eplain many of the somatic symptoms associated with panic disorder. Cholecytokinin is the primary regulator of bile. Usually bile is stimulated to flow by food stimulus. When bile flows in the absence of the food to mix with, it causes a series of polysystemic illnesses. The development of multiple system disease through abnormal CCK secretion is outlined.

Despite the inclusiveness of this chart, I feel that this only explains about half or less of what we call "panic disorder" and this model takes no real look at the physiology of agoraphobia or secondary emotional disorders.